Pathophysiology Of The Underlying Process - 1589 Words

Pathophysiology of the underlying process The pathophysiology of hypertension (HTN) is best explained clearly if you have an understanding of how blood pressure (BP) works in the body. BP is seen as the function of both cardiac output (CO) in the human system and systemic vascular resistance (SVR). Cardiac output (CO) is made up of both heart rate (HR) and stroke volume (SV). SV in turn depends on contractility and preload of the system. SVR relies on contractility and afterload. There is literature that supports molecular and cellular levels relating to effects on blood pressure in terms of genetic make-up. Changes in any of these processes have the ability to alter CO or SVR, causing BP alteration and HTN. There are two main types of HTN; the more prevalent of the two is termed essential HTN or primary HTN. This type of HTN accounts for more than 90% of diagnosed HTN in patients. This is when there is no secondary cause that is identifiable and is diagnosed in those with multiple comorbidities, insulin resistance, metaboli c syndrome, alcohol intake, age, genetic history, obesity and sedentary lifestyle. The less identifiable HTN is termed secondary HTN. This is when HTN is diagnosed through a cause that is identifiable such as: hyperthyroidism, renal diseases, aldosterone and glucocorticoid excess. HTN is one of the most preventable diseases that is responsible for deaths and a gamut of disease processes in the US. According to Joint National Committee (JNC) 8; HTN isShow MoreRelatedPsoriasis Pathophysiology Essay817 Words   |  4 PagesPsoriasis Pathophysiology Psoriasis is a common skin disorder affecting millions of people. It affects 2 to 3% of the Caucasian population, usually in individuals between 15 and 30 years old. (Liu, Krueger, Bowcock, 2007). There are several different forms of the disease. The most common type is chronic plague psoriasis. 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